9158 Research Associate I/Research Associate II
Duties:
The Cell Culture Process Development department is seeking to fill a position for a Research Associate in upstream research and development.
The successful candidate will work both independently and as part of a team focusing on optimizing production of recombinant viral vectors for the company’s gene therapy programs.
Buffer and media preparation:
Cell line maintenance, expansion, transfection Production, harvest, and purification of viral material.
Perform associated analytical assays.
Diligently document the results Maintenance of laboratory equipment.
Flexibility in a fast-paced, changing environment; be willing to accept responsibilities outside of the initial job description.
Handle multiple tasks efficiently.
Closely interact with other team members; develop internal and external collaborations.
Present results and conclusions in group and department meetings; write reports.
Skills: Required:
Good working knowledge of chemistry and biochemistry principles.
Aseptic culturing technique.
Hands-on experience in suspension or adherent cells culturing.
Critical thinking, data analysis and interpretation skills.
Good interpersonal, verbal, and written communication skills.
Proficiency in Microsoft Word, Excel, and PowerPoint.
Desired:
Experience with mammalian cell cultures, metabolite measurement, cell count and viability measurements.
Working knowledge of rAAV production process, transfection.
Experience with any of the following analytical techniques: flow cytometry, ddPCR/qPCR, Western Blotting, ELISA, Bio-Layer Interferometry (Octet), total protein assay, cell-based assays.
Knowledge of Ambr bioreactor operation is a plus.
Knowledge of JMP software and Design of Experiments principles is a plus.
Education:
Minimum:
Bachelor’s degree in biological sciences or in a related field with 2+ years of experience in a cell culture laboratory.
Preferred:
Bachelor’s degree with 4+ years or master’s degree with 2+ years of experience in industrial research and development.
PLEASE NOTE: Our client has mandated COVID-19 vaccination for their workforce, all external personnel providing services to our client are required to comply with this requirement.